Protein Ligand Affinity Databases
I came across a nice tabular summary of some existing 'public' 'primary' protein-ligand interaction databases that primarily focus on protein-ligand affinity data (so Ki, Kd, IC50, EC50, etc.), that I have reproduced below (many thanks to Helena Strömbergsson, from Uppsala University for the data).
| Name | Target Class Focus | Approx size |
|---|---|---|
| BindingDB | All | ~48,000 |
| PDSP | Receptors | ~47,000 |
| BRENDA | Enzymes | ~19,000 |
| BindingMOAD | All | ~3,500 |
| PDBBind | All | ~3,500 |
| AffinDB | All | ~700 |
| PLD | All | ~500 |
The comparable number from StARlite (31) are 507,645 (of which 186,370 are better than 100nM) for affinity class end-points. Oh, and we have started a new load.....