GPCR Structures - Agonist form of A2a PDBe:3QAK


There is a new GPCR structure available, an engineered form of human A2a complexed with an agonist ligand, the Phase 2 clinical candidate UK-432,097 (PDBe:3QAK). The paper accompanying this structure is available on the Science website.

UK-432,097

%T Structure of an Agonist-Bound Human A2A Adenosine Receptor
%A Xu F
%A Wu H
%A Katritch V
%A Han GW
%A Jacobson KA
%A Gao ZG
%A Cherezov V
%A Stevens RC
%J Science
%D 2011
%O PDBe:3qak 
%O DOI:10.1126/science.1202793

I've also updated the GPCR page with all the recent structures (there were some new beta-1 and beta-2 structures as well).