ChEMBL

Yet another GPCR structure (when I was younger, these four simple words side by side would have been unbelievable), this time of the human D3 receptor (Uniprot:P34562) at 2.9 Angstrom resolution and complexed with the antagonist Eticlopride (Chembl:CHEMBL8946), there are two molecules of D3 in the a.u. and the structure is available from public protein structure databases (PDBe:3pbl).


This makes a total of 7 distinct rhodopsin-like GPCR structures now known.

%J Science
%D 2010 
%V 330
%P 1091-1095 
%T Structure of the Human Dopamine D3 Receptor in Complex with a D2/D3 Selective Antagonist
%A E.Y.T. Chien
%A W. Liu
%A Q. Zhao
%A V. Katritch
%A G. Won Han
%A M.A. Hanson
%A L. Shi
%A A. Hauck Newman
%A J.A. Javitch
%A V. Cherezov
%A R.C. Stevens