June 2010 proposed INNs for protein kinase inhibitors


There is a new clutch of proposed protein kinase inhibitor INNs. These are:

Amuvatinib aka MP-470 and HPK-46, SuperGen's FLT3 inhibitor 
S=C(NCc2ccc1OCOc1c2)N6CCN(c4ncnc5c3ccccc3oc45)CC6


Crizotinib aka PF-2,341,066, Pfizer's ALK and MET inhibitor 
C[C@@H](Oc3cc(c2cnn(C1CCNCC1)c2)cnc3N)c4c(Cl)ccc(F)c4Cl


Dacomitinib aka PF-299,804 - Pfizer's EGFR, and HER2 inhibitor 
COc3cc2ncnc(Nc1ccc(F)c(Cl)c1)c2cc3NC(=O)C=CCN4CCCCC4


Orantinib aka SU-6,668, Pfizer's Aurora, FGFR, VEGFR, and PDFGR inhibitor 
Cc3[nH]c(C=c1c(=O)[nH]c2ccccc12)c(C)c3CCC(=O)O


Ruxolitinib aka INCB-18,424, Incyte's JAK2 inhibitor 
C#CC[C@H](C1CCCC1)n4cc(c2ncnc3[nH]ccc23)cn4



Silimitasertib aka CX-4,945, Cylene's CK2 inhibitor 
O=C(O)c1ccc4c(c1)nc(Nc2cccc(Cl)c2)c3ccncc34


Tivantinib aka ARQ-197, Arqule's MET inhibitor 
O=C4NC(=O)[C@@H](c1cn3CCCc2cccc1c23)[C@@H]4c5c[nH]c6ccccc56