INNS for kinase inhibitors

INNS for kinase inhibitors - October 2010

12 Oct 2010

There is another clutch of protein kinase inhibitors (nine) in the latest list of recommended INNS, these are:

Afatinib a.k.a. BIBW-2992 - Boehringer-Ingelheim's EGFR and HER2 inhibitor.

Barasertib a.k.a. AZD-1152 - AstraZeneca's Aurora kinase inhibitor.

Dilmapimod a.k.a. GW-681323, SB-681323 - GSK's p38alpha inhibitor.

Dinaciclib a.k.a. SCH-727965 - Merck's CDK1, CDK2 CDK5 and CDK9 inhibitor.

Foretanib, a.k.a. GSK-1363089, XL-880 - GSK's KIT MET FLT3 PDGFRa PDGFRb TIE2 VEGFR1 VEGFR2 VEGFR3 inhibitor.

Linifanib a.k.a. ABT-869 - Abbott's FLT3 CSF1R VEGFR2 inhibitor.

Tivozanib a.k.a. AV-952 - Aveo's VEGFR1 VEGFR2 VEGFR3 inhibitor.

Varlitinib a.k.a. ARRY-543 - ARRY-334543, ArrayBiopharma's EGFR HER2 inhibitor.

Volasertib a.k.a. BI-6727 - Boehringer-Ingelheim's PLK1 inhibitor.