• Hit the sack - Pt. I - Down Hall, Herts, UK

    Part of an irregular, but useful review of hotels, etc., that I have used, and a rating for the visiting scientist. The first of the list is Down Hall, near Bishops Stortford in the U.K. Overall, a 43% score.

  • Room quality - 6/10
  • Cost - I did not pay so no score
  • Phone reception - 1/10 (pretty dire, on O2 at least)
  • Internet - 3/10 (7.50GBP per day)
  • Conference facilities - 7/10
  • Mushroom factor - 4/10 (mostly ornamental non-native trees, so pretty barren, but a nice stinkhorn or two in the grounds)

  • Licensing of ChEMBL Data - RFC

    I have been thinking long and hard about the actual process for the public distribution of the ChEMBL data, and nothing is decided yet; however, I think it is likely that there will be a license for the distribution. In line with some of the existing 'free' EMBL-EBI resources, this is likely to take the form of one of the Creative Commons licenses (see http://www.creativecommons.org for more details. So as a question, what experience do people have with these licenses, as applied to public domain databases?

    Oh, The license we are most like to use is.....  Basically this allows redistribution and the production of derivative works, while applying conditions that attribution must be provided, and that any derivative works will be similarly shared.

  • ChEMBL Logo?

    As a group, we have been thinking about our identity and branding, and (with pride) display our likely logo for the ChEMBL group. It is meant to strongly echo the existing EBI house logos, while giving a clear chemocentric identity..... Enough waffle, here is the logo.

  • Conference - Indiana Chemoinformatics Meeting - 11th December

    Chris Steinbeck and I are off to the eScience for Chemoinformatics and Drug Discovery Meeting on the 11th December in Bloomington Indiana. Link to conference website. This should be fun, and I will try and fix up a few meetings around this. Too bad the pound is so weak against the dollar now. However, looking for 'shrooms is free, so I will try and take a days holiday while out there to try and find something interesting.

  • www.overingtonlab.org is live!

    So, following in the footsteps of some of my friends (http://www.salilab.org and http://www.hopkinslab.org), I have set up http://www.overingtonlab.org

  • Books and Papers - 0 - Links to some ChEMBL papers and posters

    I have had a couple of recent emails requesting copies of papers, here are some pdfs. 

    %O PMID 17139284
%V 5
%D 2006
%T How many drug targets are there?
%P 993-6
%A Overington, John P
%A Al-Lazikani, Bissan
%A Hopkins, Andrew L
%J Nat Rev Drug Discov
    Nature Reviews Drug Discovery - Drug Target Poster
    Nature Reviews Drug Discovery - Drug Target Paper 

    %O PMID -  18927591
%V 7
%D 2008
%T Genomic-scale prioritization of drug targets: the TDR Targets database
%P 900-7
%A Aguero, Fernan
%A Al-Lazikani, Bissan
%A Aslett, Martin
%A Berriman, Matthew
%A Buckner, Frederick S
%A Campbell, Robert K
%A Carmona, Santiago
%A Carruthers, Ian M
%A Chan, A W Edith
%A Chen, Feng
%A Crowther, Gregory J
%A Doyle, Maria A
%A Hertz-Fowler, Christiane
%A Hopkins, Andrew L
%A McAllister, Gregg
%A Nwaka, Solomon
%A Overington, John P
%A Pain, Arnab
%A Paolini, Gaia V
%A Pieper, Ursula
%A Ralph, Stuart A
%A Riechers, Aaron
%A Roos, David S
%A Sali, Andrej
%A Shanmugam, Dhanasekaran
%A Suzuki, Takashi
%A Van Voorhis, Wesley C
%A Verlinde, Christophe L M J
%J Nat Rev Drug Disco

    Nature Reviews Drug Discovery - WHO-TDR Paper

  • Conference - RSC/Biochem Soc Conference ChEMBL Presentation - 28th November

    I have been invited to present at a joint Biochem Soc/Royal Society of Chemistry meeting in London, on Integration of Drug Discovery and Systems Biology' at Burlington House on the 28th November. I will try and present some new stuff there, if I get the chance to put together some nice slides - hopefully the assay clustering stuff is lying around somewhere. But again it looks an excellent meeting, worth attending for the other talks. Link to conference website

  • Beerlgium presentation - 30th October

    I am off to Brussels on the 30th October to speak at the excellent looking Be Live IT conference. I will outline the new ChEMBL resources, and hopefully also present some of the differences between the private and public funded sectors for this field. The speakers after me look very good. Link to conference website