ChEMBL

There's a great paper just published in NRDD on the analysis of potential drug targets using an objective, evidence-based approach, it makes extensive use of ChEMBL data, alongside specific cancer-related datasets, pathway and interaction data and so forth. There is also some good discussion of drug-repurposing informatics approaches.

A link to the pdf of the paper is here.

%T Objective assessment of cancer genes for drug discovery
%A M.N. Patel
%A M.D. Halling-Brown
%A J.E. Tym
%A P. Workman
%A B. Al-Lazikani
%J Nature Reviews Drug Discovery
%V 12
%P 35-50
%D 2013
%O doi:10.1038/nrd3913

Disclosure - one of the authors of the above paper (Al-Lazikani) is my wife.

jpo