ChEMBL

There are clearly some advantages in pooling or analysing website search data - it highlights interesting trends, something becoming more interesting to a user community can spot emerging events, etc. It can alert to flu outbreaks (there was a Science paper from google on this, don't have the reference handy though - you may be able to find it with google though.....). There is a huge interest in many sites that I use in tracking and analysing query terms and usage patterns, and in some contexts this is just the thing to do - like when ebay teases me (and surely of all the tortured obsessive souls on the planet, it is just me and me alone) with a rare phosphor or perforation machin variant I don't have.

The types of query that people perform can clearly also be used to develop ways of improving a website, or specifically the performance of search queries - and for algorithm development this information can be like gold-dust. There are now many chemical fingerprint systems available, and adapting the features/structures of these to typical user queries is really valuable in their development.

There are essentially two distinct aspects to user's expectations/rights of privacy when using a website like ChEMBL.

• There is a personal privacy issue - 'why is John Overington interested in compounds for the treatment of obesity?'. This is an primarily an embarrassment sort of thing ('hey, is this guy a bit chubby?'), or maybe a commercially sensitive thing ('he's interested in obesity stuff; heh, let's raise the price for him', or 'let's show him some adverts for chips', or 'let's contact his rival and let them know he's interested in his weight'). These latter things are behind the feature where you first search for a flight and the price is great, then the next time you look, it's gone up - allegedly.
• There's a more fundamental IP issue though -  The simple disclosure of a search term can be commercially damaging, and potentially stop the development of life-saving therapies. The simplest case is chemical structure and drug patents. The most important patent claim in drug discovery is to have composition of matter (and don't get all hissy over pharma misusing the patent system, since patents are absolutely essential for the development of new medicines, the treatment of disease, improvement of food supplies, for funding future R&D, for a source of employment, license revenues to Universities, and taxation revenues, etc). This composition of matter is a claim of a novel chemical structure, that no-one has disclosed before, and it is useful for something. If the structure is not novel, then the patent can be readily invalidated.