ChEMBL

There's now a BioRuby API for ChEMBL, written by the excellent Mitsuteru Nakao (@32nm on twitter). Bio-chembl is a bioruby plugin built on top of the ChEMBL REST web services - https://github.com/nakao/bio-chembl

Of course, there is also the pychembl project in Python from Marcus Sitzmann of the NCI. - https://github.com/markussitzmann/pychembl

And I've just been reminded of the R ChEMBL package from Rajarshi Guha - https://github.com/rajarshi/chemblr 

However, the real mark of success will be when we get a ChEMBL f77 library!