Some New GPCR Structures (Coming)

08 Apr 2012

I still get excited when a new set of interesting coordinates get released in PDBe - I hope I never stop getting this thrill from ~300 Kbytes of 3-D coordinates. Anyway, I'm packing my bag to return from an excellent conference/advanced school in Brazil, and I thought I'd spend a little time browsing some of my regular sites. One of these was the GPCR Network page, and it looks like there are two more GPCR structures to be released soon (or at least solved)!! It's such a tease to have an image of the structures on that page - so now I'll be regularly checking the usual suspect journals for the pre-press papers.....

The new ones appear to be the Nociceptin receptor (UniProt:P41146), and the Muscarinic M1 receptor (UniProt:P11229). Note I don't know that the structures are of the human receptor, but the UniProt links are for the human orthologue).

Can't wait.