Update of Chemistry Follow-up on GSK Malaria HTS set
Here is an update on some follow-on chemistry on the GSK Malaria screening set, provided by the researchers at GSK's Tres Cantos Medicines Development Campus.
Chemistry in progress
TCMDC-123822, TCMDC-123823, TCMDC-123824, TCMDC-123827, TCMDC-134513, TCMDC-123579, TCMDC-123582, TCMDC-125454, TCMDC-134141, TCMDC-134142, TCMDC-134143, TCMDC-134692, TCMDC-135254, TCMDC-135271, TCMDC-135426, TCMDC-135461, TCMDC-135462, TCMDC-135463, TCMDC-135554, TCMDC-135654, TCMDC-135655, TCMDC-135656, TCMDC-135657, TCMDC-135677, TCMDC-135687, TCMDC-135789, TCMDC-135796, TCMDC-135816, TCMDC-135911, TCMDC-136013, TCMDC-136014, TCMDC-136015, TCMDC-136016, TCMDC-136051, TCMDC-136060, TCMDC-136134, TCMDC-136185, TCMDC-136188, TCMDC-136303, TCMDC-139046
Chemistry on hold
TCMDC-123540, TCMDC-123620, TCMDC-123685, TCMDC-123755, TCMDC-123796, TCMDC-123825, TCMDC-124434, TCMDC-124501, TCMDC-125331, TCMDC-125334, TCMDC-125650, TCMDC-134557, TCMDC-134672, TCMDC-134674, TCMDC-134675, TCMDC-135196, TCMDC-135265, TCMDC-135371, TCMDC-135510, TCMDC-135533, TCMDC-135572, TCMDC-135650, TCMDC-135652, TCMDC-135659, TCMDC-135672, TCMDC-135684, TCMDC-135696, TCMDC-135772, TCMDC-135797, TCMDC-135803, TCMDC-135804, TCMDC-136325, TCMDC-136326, TCMDC-136328, TCMDC-136760, TCMDC-136761, TCMDC-136807
Chemistry abandoned
TCMDC-123822, TCMDC-123823, TCMDC-123824, TCMDC-123827, TCMDC-134513
We'll put this data into the ChEMBL-NTD microsite shortly, but if any other groups have updates on the Malaria screening data disclosures, or various analyses that we could point to, we'd be very happy to hear.
If you want to link directly to a particular TCMDC number you can use a url of the form...
https://www.ebi.ac.uk/chemblntd/system_search?qString=TCMDC-136165